High-Field NMR Facility

High-Field NMR Facility at NINT


NMR spectroscopy can provide a wealth of information about the nature of solute molecules and solute-solvent interactions. NMR has been widely used in a variety of areas:

  • Determine Solution Structure of Small Molecules
  • DNA and Protein Structure Determination
  • Molecular Dynamics
  • Diffusion Measurements
  • Hydrogen Bonding Determination/pKa Measurements
  • Drug Screening
  • Metabolite Analysis -Metabolomics
  • Natural Product Chemistry
  • Polymer Chemistry
  • Environmental Chemistry

The space

Located at the second floor of NINT building, the NINT High-Field NMR facility consisting of a VNMRS 600 MHz spectrometer provides access to state-of-the-art NMR instrumentation.


VNMRS 600 Spectrometer overview

  • 14.1 Tesla or 600 MHz for 1H
  • 3 RF-channel “Direct Drive” console
  • Varian 5mm z-PFG AutoX DB probe for high frequency (1H—19F, 560-610 MHz) and low frequency (15N— 31P, 60-250 MHz) observe and decouple, Z-axis PFG (max. gradient strength 22G/cm)
  • ProTune automated probe tuning/matching: tuning from the keyboard
  • Automated deuterium locking
  • Automated deuterium gradient shimming
  • Variable temperature control (-20℃ to +80℃)
  • Z-axis pulsed field gradients
  • DOSY diffusion correlation spectroscopy software
  • VnmrJ 2.2C + ChemPack 4.1 software (Red Hat Linux 5.6)
  • HP Laser Jet 2420 (8.5 x 11)